Figure 3.

Death ligands stimulate human preadipocyte proliferation. A) SGBS preadipocytes were stimulated with growth medium alone or with increasing doses of either FasL or TNF-α. After 72 hours, [³H]-thymidine incorporation was measured. Data are expressed as means ± sem of 3 independent experiments performed. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001 compared with growth medium alone. B) SGBS preadipocytes were stimulated with growth medium alone or with either TRAIL or increasing doses of IGF-1. After 72 hours, [³H]-thymidine incorporation was measured. Data are expressed as means ± sem of at least 3 independent experiments performed. ***P ≤ 0.001 compared with growth medium alone.