Table 1.
Intersoftware intraclass correlation coefficients (ICCs).
| Metric | ICC (95% CI) | ||
|---|---|---|---|
| Agreement | Consistency | ||
| Operator 1 | Mean rCBV | 0.804 (0.642, 0.893) | 0.848 (0.766, 0.908) |
| 95% rCBV | 0.683 (0.309, 0.849) | 0.818 (0.722, 0.888) | |
| % voxels above NAWM | 0.679 (0.330, 0.842) | 0.804 (0.704, 0.879) | |
| Operator 2 | Mean rCBV | 0.756 (0.591, 0.859) | 0.800 (0.698, 0.877) |
| 95% rCBV | 0.718 (0.421, 0.859) | 0.817 (0.721, 0.887) | |
| % voxels above NAWM | 0.642 (0.269, 0.823) | 0.787 (0.680, 0.868) | |
| Operator 3 | Mean rCBV | 0.811 (0.653, 0.897) | 0.853 (0.774, 0.911) |
| 95% rCBV | 0.721 (0.430, 0.859) | 0.817 (0.721, 0.887) | |
| % voxels above NAWM | 0.657 (0.257, 0.838) | 0.811 (0.713, 0.884) | |
Note: CI, confidence interval; rCBV, relative cerebral blood volume; NAWM, normal-appearing white matter; Agreement: Comparison of raw values; Consistency: Comparison of values with software-specific means subtracted.