Table 1.

Measurements on three leg muscles, expressed in terms of fat/metabolite ratios, pennation angle, IMCL–EMCL chemical shift, and fat fractions.

Quantity	Tibialis anterior (TA)	Soleus (SO)	Vastus lateralis (VL)
IMCLa	$2.33\pm 0.19$	$8.66\pm 1.24$	$6.12\pm 0.77$
	(1.11 to 3.36)*†	(3.21 to 18.28)	(2.10 to 11.34)
IMCLb	$2.38\pm 0.18$	$9.11\pm 1.41$	$5.95\pm 0.71$
	(0.95 to 3.56)†	(3.08 to 21.33)	(2.37 to 10.85)
Total lipida	$11.06\pm 2.70$	$36.66\pm 2.74$	$23.95\pm 2.92$
	(3.28 to 36.07)*†	(24.34 to 53.80)	(5.37 to 39.66)
Total lipidb	$11.09\pm 2.14$	$36.97\pm 3.07$	$22.47\pm 3.12$
	(3.54 to 28.77)*†	(25.66 to 57.74)	(5.78 to 42.77)
Pennation angle ($\theta$)	$8.49\pm 1.04$	$17.06\pm 1.59$	$23.78\pm 5.63$
	(2.20 to 14.62)*†	(11.26 to 31.92)	(8.52 to 30.94)^
Chemical shift ($\delta$)	$0.19\pm 0.01$	$0.17\pm 0.01$	$0.15\pm 0.01$
	(0.18 to 0.20)	(0.12 to 0.18)	(0.12 to 0.19)^
${}^1\mathrm{H}\text{-}\mathrm{MRS}$ FF (%)	$1.71\pm 0.18$	$3.19\pm 0.23$	$2.30\pm 0.22$
	(0.68 to 3.15)*†	(2.15 to 4.63)	(1.33 to 3.61)^
MRI FF (%)	$1.85\pm 0.12$	$3.17\pm 0.22$	$2.51\pm 0.17$
	(1.40 to 3.06)*†	(1.86 to 4.82)	(1.73 to 3.86)^

Note: $N=12$. Lipid concentration expressed in $\mathrm{mmol}/\mathrm{kg}\mathrm{ww}$. ^*SO versus TA, $p<0.001$; ^†VL versus TA, $p<0.05$; ^VL versus TA, $t$-test comparisons, $p<0.05$.

^aIMCL and total lipid—measured using internal water as reference.

^bIMCL and total lipid—measured using muscle creatine as internal reference.