Table 2.

Quantitative evaluation of CBRR and comparison to group-wise registration on the three-dimensional (3-D) CT dataset. Mean TRE, mean surface distance (MSD), Hausdorff distance (HD), and inconsistency $\mathcal{C}$ are given in mm.

	3-D CT
	TRE	Dice	MSD	HD	$\mathcal{C}$	Total run time (h)
Reg-demons	$9.25\pm 4.22$	$0.65\pm 0.15$	$1.27\pm 1.19$	$17.86\pm 8.83$	8.14	140
+ CBRR	$7.16\pm 2.19$	$0.75\pm 0.09$	$0.58\pm 0.36$	$14\pm 5.65$	1.07	$+2.5$
Reg-MRF	$5.25\pm 1.95$	$0.84\pm 0.06$	$0.34\pm 0.29$	$11.43\pm 4.86$	5.67	39
+ CBRR	$\mathbf{4.66}\pm 1.20$	$0.86\pm 0.03$	$0.22\pm 0.10$	$9.72\pm 3.65$	1.12	$+2.5$
Reg-ANTs	$6.02\pm 3.35$	$0.85\pm 0.11$	$0.49\pm 0.68$	$12.27\pm 5.99$	6.43	105
+ CBRR	$4.70\pm 1.60$	$\mathbf{0.89}\pm 0.04$	$\mathbf{0.17}\pm 0.12$	$\mathbf{8.79}\pm 3.48$	1.13	$+2.5$
Group-wise reg.	$8.1\pm 2.86$	$0.75\pm 0.10$	$0.97\pm 0.61$	$22.64\pm 4.30$	0.0	26

Note: ANTs, advanced normalization tools; Bold numbers indicate best results in each category.