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Outcomes and estimates of the probability of dose-limiting toxicity at each study dose level
| Dose level | Cixutumumab weekly dose (mg/kg) | Prior estimate for DLT (%) | Patients treated | Patients with DLT (s) | Posterior estimate for DLT (%) | 95% Bayesian credible interval (%) |
|---|---|---|---|---|---|---|
| A | 1 | 10 | 4 | 0 | 4.5 | 1.0–14.1 |
| B | 3 | 13 | 13 | 1 | 6.2 | 1.6–17.8 |
| C | 6 | 18 | 12 | 1 | 9.4 | 2.7–23.6 |
