Figure 3.
djr deletion-dependent lifespan alteration in response to Mn treatment. A) djr deletion does not affect lifespan under control conditions; (B) djr-1.2 deletion mutants show increased sensitivity to 50mM Mn when compared to N2 (wt) animals (p<0.01) (C) djr-1.2 deletion mutants show reduced lifespan after acute Mn exposure (p<0.01). Lifespans were compared with the log-rank test (n=30).