Table 3.
Multivariate model predicting % fPSA
| Change in Predicted %fPSA Mean (95% CI) |
p Value* | ||
|---|---|---|---|
| Age (per 5-yr increase) | −0.3 | (−0.5, −0.05) | 0.021 |
| Race/ethnicity: | 0.048 | ||
| NonHispanic white | 0 | (reference) | |
| NonHispanic black | −0.4 | (−1.8, 0.9) | |
| Mexican-American | −3.2 | (−4.8, −1.7) | |
| Other | −1.3 | (−4.4, 1.7) | |
| Smoking status: | 0.015 | ||
| Current smoker | −1.2 | (−2.8, 0.4) | |
| Former smoker | 1.2 | (−0.1, 2.5) | |
| Never smoker | 0 | (reference) | |
| BMI (per 5 kg/m2 increase) | 0.0 | (−0.6, 0.5) | 0.926 |
| Diabetes: | 0.003 | ||
| No | 0 | (reference) | |
| Yes | 3.8 | (1.4, 6.2) | |
| BPH: | 0.145 | ||
| No | 0 | (reference) | |
| Yes | −1.4 | (−3.4, 0.5) | |
| Statin use: | 0.812 | ||
| No | 0 | (reference) | |
| Yes | −0.2 | (−1.6, 1.2) | |
| NSAID use:† | 0.287 | ||
| No | 0 | (reference) | |
| Yes | 1.2 | (−1.0, 3.4) | |
| Thiazide diuretic use: | 0.151 | ||
| No | 0 | (reference) | |
| Yes | 1.5 | (−0.6, 3.7) | |
| C-reactive protein‡ | Nonlinear (nonlinear) | <0.001 | |
All variables included in the model are shown in the table.
*
Based on the F-statistic with Satterthwaite correction for the degrees of freedom from the simultaneous test that all coefficients for a given variable are equal to 0.
†
Prescription only.
‡
Increasing C-reactive protein was associated with a decrease in %fPSA for levels up to 0.7 mg/dl. Above this level there was no relationship between C-reactive protein and %fPSA.