Fig. 4.

CD24⁻ cells construct the bulk of the tumors cells originating from both CD24⁻ and CD24⁺ cells. a Experimental strategy scheme. Green fluorescent protein (GFP)⁺ CD24⁻ or CD24⁺ cells were injected into the mammary fat pads. Tumors were harvested and CD24 expression was evaluated in GFP⁺ cancer cells. b CD24 and CD49f expression in GFP⁺ cancer cells from mammary tumors was determined by fluorescence-activated cell sorting (FACS) analysis