Figure 5.

Probability that a population will follow a certain mutational trajectory as a function of population size. Shown are data for the landscape in Fig. 1 excluding back-mutations with a mutation rate of μ = 10⁻³ and epistatic replication rates of r₀ = 0, r₁ ≈ 0.049, r₂ ≈ 0.010, r₃ ≈ 0.002, r₄ ≈ 0.012, r₅ ≈ 0.051, r₆ ≈ 0.059, and r₇ ≈ 0.061. Equation 37 (solid lines) predicts the asymptotic behavior of the simulation values — N₁₂₃(×), N₂₁₃(엯), N₁₃₂(◻), N₃₁₂(+), N₂₃₁(*), N₃₂₁(◇) — for large population sizes. The second order expansion (dashed lines) improves the prediction for sufficiently large populations. The error bars are one standard error.