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Mutations introduced into the α4β7 binding motif of T/F viruses
| Individual | Type | α4β7 binding motifa | IEC |
|---|---|---|---|
| CAP225 T/F | Wild type | SDI | ✓ |
| Mutant | LDI | Did not grow | |
| CAP88 T/F | Wild type | PDI | ✓ |
| Mutant | LDI | Did not grow | |
| CAP200 T/F | Wild type | SDV | ✓ |
| Mutant | LDI | Did not grow | |
| CAP8 T/F | Wild type | LDI | ✓ |
| Mutant | PDI | ✓ | |
| CAP256 T/F | Wild type | LDL | ✓ |
| Mutant | SDI | ✓ |
aIntroduced mutations are in italics.
