Table 1.
Effect of D-mannitol, pectin, and praziquantel on the levels of glucose and glycogen in Schistosoma mansoni-infected mice liver.
| GROUPS | CONTROL GROUPS | INFECTED GROUPS | TREATED GROUPS | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PARAMETER | CONTROL | CONTROL CONS.1 | CONTROL CONS.2 | CONTROL PZQ | 6 WEEKS | 10 WEEKS | 14 WEEKS | CONS.1 4 WEEKS | CONS.1 8 WEEKS | CONS.2 4 WEEKS | CONS.2 8 WEEKS | PZQ |
| T. protein | 103.1 ± 2.11a | 97.76 ± 0.9a–c | 95.06 ± 0.57b,c | 97.09 ± 29a–c | 80.55 ± 3.64d | 63.79 ± 4.765e | 55.08 ± 4.67f | 93.71 ± 2.87c | 101.8 ± 1.75a,b | 90.90 ± 1.89c | 96.64 ± 1.47a–c | 92.36 ± 2.11c |
| Glucose | 7.15 ± 0.38a | 6.83 ± 0.33a,b | 6.86 ± 0.32a,b | 6.78 ± 027a,b | 4.77 ± 0.30f | 4.07 ± 0.41g | 3.54 ± 0.36h | 5.80 ± 3.20d | 6.32 ± 0.21c | 5.37 ± 0.43e | 5.60 ± 0.23d,e | 6.50 ± 0.29b,c |
| Glycogen | 6.43 ± 0.34a | 6.24 ± 0.40a,b | 6.25 ± 0.38a,b | 6.10 ± 024a,b | 4.30 ± 0.27e | 3.68 ± 0.39f | 3.11 ± 0.32g | 5.22 ± 0.29d | 5.70 ± 0.19c | 4.60 ± 0.50e | 5.04 ± 0.21d | 5.84 ± 0.25b,c |
Notes: Data are expressed as means ± SD of eight mice in each group. Values of T. protein are expressed as mg/g tissue, and those of glucose and glycogen are expressed as μg/g tissue, p is level of significance, where p < 0.0001 is significant. Analysis of data is carried out by one-way (ANOVA) (analysis of variance) accompanied by post hoc (LSD) (Least significant difference) (CoStat Computer program). Cons.1 means D-mannitol costituent of Ixora undulata Roxb. Leaves; Cons.2 means pectin constituent of Linum grandiflorum Desf. leaves; and PZQ means praziquantel, administered as a double dose.
Unshared letters indicate that these groups are significantly correlated at P < 0.05 while shared letters indicate that these groups are non-significantly. ANOVA p < 0.0001.