Fig 3. Disease development, movement of Xf and therapeutic efficacy of phage cocktail.
(A,B) Quantitative levels of Xf-T1 at week 8 (A) and 12 (B) post-inoculation of grapevines with only Xf-T1 (White bars) (symptoms Fig 2A and 2B, respectively) or Xf-T1 and treated with phage cocktail at week 3 post-Xf-T1 inoculation (Grey bars) (symptoms Fig 2H and 2I, respectively). POI (indicated with arrows) and grapevine segments numbered as POI (0), below (-) or above (+) in ~13 cm segments. Root divided into three segments and numbered as R0, R-1, or R-2. Segments of similar proximal distance from the graft point from triplicate grapevines were assayed using qRT-PCR to determine the mean CFU/gt ± s.d. Each bar represents s.d. Significant differences are noted by asterisks (*). qRT-PCR line plots obtained for Xf-T1 had R2 values of greater than 0.9 and efficiencies of 157%.