Tab. 2.

Inhalant mammalian allergens that have been characterized (modified according to [8]). All allergens listed are also officially listed in the WHO/IUIS allergen database (www.allergen.org)

Animal species	Allergen	Protein family	MW (kDa)	Allergen source	Sensitization (%)*
Cat (Felis domesticus)	Fel d 1 Fel d 2 Fel d 3 Fel d 4 Fel d 5 Fel d 6 Fel d 7 Fel d 8	Secretoglobin Serum albumin Cystatin Lipocalin IgA IgM Lipocalin Latherin	18 69 11 22 400 800–1000 18 24	Saliva, dander Serum, skin Dander Saliva Saliva, serum Serum Saliva	60–100 14–23 10 63 38 - 38 19
Dog (Canis familiaris)	Can f 1 Can f 2 Can f 3 Can f 4 Can f 5 Can f 6	Lipocalin Lipocalin Serum albumin Lipocalin Kallikrein Lipocalin	23–25 19 69 18 28 27–29	Saliva, dander Saliva, dander Serum, skin, saliva Saliva, dander Urine Saliva, dander	50–75 22–30 25–35 35 70 61
Horse (Equus caballus)	Equ c 1 Equ c 2 Equ c 3 Equ c 4	Lipocalin Lipocalin Serum albumin Latherin	22 17 67 17–19	Dander, saliva Dander Serum, skin Dander, saliva	76 50 18–50 77
Cow (Bos domesticus)	Bos d 2 Bos d 3 Bos d 6	Lipocalin Calcium-binding protein Serum albumin	20 11 67	Hair, dander Hair, dander Serum, Haut	>90 43 -
Rabbit (Oryctolagus cuniculus)	Ory c 1 Ory c 3 Ory c 4	Lipocalin Secretoglobin Lipocalin	17–18 19–21 24	Saliva, dander Saliva, dander Saliva	- 77 46
Rat (Rattus norvegicus)	Rat n 1	Lipocalin	17	Urine	73–87
Mouse (Mus musculus)	Mus m 1	Lipocalin	17	Urine	66
Guinea pig (Cavia porcellus)	Cav p 1 Cav p 2 Cav p 3 Cav p 4 Cav p 6	Lipocalin Lipocalin Lipocalin Serum albumin Lipocalin	20 17 18 66 18	Hair, urine Saliva, hair Saliva, hair Serum Saliva	70 65 54 52 -

MW, molecular weight; —, no information available

* Sensitization rates are based on a number of studies with different patient groups and test systems (enzyme linked immunosorbent assay [ELISA], Immunoblot, ImmunoCAP®, skin test). Thus they represent merely a guide and not absolute figures.