Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jun 24;10(6):e0129252. doi: 10.1371/journal.pone.0129252

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Pant et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Fig 3 — Previously published transcriptome profile of OSF tissues (GSE 20170) [6] was compared with that of areca nut and/ or TGF-β regulated transcriptome in HaCaT (GSE 38227) [10] and hGF cells. a & b] Venn diagram and hierarchal cluster representing distribution of differentially or commonly regulated genes by areca nut in HaCaT cells and OSF. c & d] Venn diagram and hierarchal cluster representing distribution of differentially or commonly regulated genes by TGF-β in HaCaT cells and OSF. e] Venn diagram represents the 252 genes common between the 362 (252+104) genes regulated by areca nut in HaCaT and OSF and the 731 (252+ 473) genes regulated by TGF-β in HaCaT cells and OSF. f] Out of the 252 genes discussed in 3e, 182 genes are not regulated by areca nut in presence of ALK5 inhibitor (SB 431542) in HaCaT cells. This indicates that these 182 genes are regulated by areca nut are via TGF-β in HaCaT cells and possibly in OSF. In all hierarchal clusters; red, green and black colours represent up, down and un-regulated genes respectively. The rows represent genes and columns represent OSF and various treatments of areca nut (5H; 5 μg/ml) and/or TGF-β (T; 5 ng/ml).