Table 5. Gene Set Enrichment analysis of differentially regulated genes in hGF cells by areca nut and TGF-β.

S. No.	Positively Enriched Pathways	Number of Genes	S. No.	Negatively Enriched Pathways	Number of Genes
1.	Focal Adhesion	114	1.	Spliceosome	86
2.	Neuroactive Ligand Receptor Interaction Pathway	99	2.	Ribosome	56
3.	Hypertrophic Cardiomyopathy HCM	51	3.	NOD Like Receptor Signaling Pathway	40
4.	Dilated Cardiac Myopathy	49	4.	Antigen Processing and Presentation	33
5.	Gap Junction	47	5.	RIG I Like Receptor Signaling Pathway	28
6.	Arrythmogenic Right Ventricular Cardiomyopathy ARVC	44	6.	Proteasome	28
7	ECM Receptor Interaction	42	7	Complement and Coagulation Cascades	26
8	Glycolysis Gluconeogenesis	33	8	Cytosolic DNA Sensing Pathway	20
9	Basal Cell Carcinoma	24
10	Fructose and Mannose Metabolism	19
11	Pentose Phosphate Pathway	16