Table 6.

Indications for AIT with allergens ^a

Verification of an IgE-mediated sensitization (preferablyb from skin testing andc/ord in vitro diagnostics) with a clear relationship to clinical symptoms (if indicated, challenge testing)

Availability of standardized or high-quality allergen extracts

Proof of efficacy of the planned AIT for the respective indication and age group

Allergen avoidance not possible or inadequate

Patient age ≥ 5 years

^a All points should be fulfilled. ^b In Switzerland, verification of sensitization preferably by skin testing.

^c “And” refers to rare allergens or uncertain results. ^d “Or” refers to situations in which skin testing is not possible and to diagnostic work-up in children below 5 years.