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. 2015 Jun 24;10(6):e0128131. doi: 10.1371/journal.pone.0128131

Table 3. Mutations shown at failure in the reverse transcriptase and protease, and NRTI included in the regimen together with NVP and TDF (3TC vs FTC).

3TC/FTC Reverse transcriptase Protease
FTC A62V,K65R,Y181C,M184V None
FTC A62V, K65R, V75I, K103N, Y181C, M184V, M230L, L63P
3TC A62V,L74V,K103N,V106A,M184V,T215S,P225H L63P
3TC A62V, K65R, K101Q, Y181C K20M, M36I, M46I, Q58E, L63P, L90M, I93L
3TC V118I, M184V, Y188C L63P
FTC M41L, E44D, D67N, K70R, M184V, T215Y, K219Q L63P
3TC Y181I, M184V G16E
3TC M41L,A62V,T69N,K70R,K103N,V108I,M184V,T215F,K219E R41K, L63P, A71V, V77I, L90M, I93L
3TC D67N, K103N, Y181C, M184V, K219E I62V, I64V
3TC None L63P
3TC A62V, K65R, A98G, Y181C, M184V L63P
3TC K65R, M184V, Y188L I15V,V77I, I93L
FTC None (wild-type) V77I
FTC L74V/L, Q102K/R, K103K/N, D177E/G, Y181Y/D, M184V, G190G/A K20R, M36I, L63P
3TC K65R, V108I, Y181C, M184V 13V, K20T, V32I, E35D, M36I, K43T, M46I, I47V, F53L, L63P, I66F, A71V, G73S, V77I, L90M,
3TC M41L, E44D, D67N, T69D, V118I, Y181C, M184V, G190A, L210W, T215Y, V106V/I, F227F/I L33V
3TC None M36I,L63P,V77I
3TC K103N/S,Y181C,M184V L33V, R41K, I64V, I13V/I, L63P
FTC K101E, G190A, K238T L10V, I13V, L63P
3TC None I13V, M36I, L63P
3TC M41L, M184V, L210W, T215Y V118I
3TC None I13V, L63P, V77I
3TC K65R, V106A, M184V None