Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic diagram of GABA metabolism and the mTOR pathway. L-His, L-histidine; mTOR, mechanistic target of rapamycin; VGB, vigabatrin; GAD, glutamic acid decarboxylase; GABA-T, GABA-transaminase; SSA, succinic semialdehyde; GHB, gamma-hydroxybutyrate; SSADH, succinic semialdehyde dehydrogenase (the site of the defect in patients with inherited γ-hydroxybutyric aciduria [box]). S6 kinase (S6K) is a mammalian kinase activated by mTOR signaling.
