Figure 5.

CD8⁺ TRAV1–2⁺ T cells with CD26^hi expression are absent in the blood of individuals with active tuberculosis (TB). (a) Contour plots displaying CD161 and CD26 expression show reduced frequencies of CD8⁺ TRAV1–2⁺ CD26^hi CD161^hi cells from three individuals with active TB and the presence of a CD26^hi CD161^dim population. (b) Frequencies of CD26^hi or CD150⁺ or CD161^hi on CD8⁺ TRAV1–2⁺ cells from the peripheral blood mononuclear cells of uninfected (n = 6), active TB (n = 3), and latent TB infection (n = 3) donors. The unpaired two-tailed, t-test was used to determine significant differences between groups, *P < 0.05; **P < 0.01.