MA enhanced the adipogenic differentiation of adipose-derived stem cells (ASCs). (A): MA significantly increased Oil Red O staining and lipid accumulation in adipogenic induction medium that did not contain Dex, but the adipogenic effect was inferior to Dex. (B): MA and Dex significantly upregulated adipogenic marker genes such as ADIPOQ, C/EBP-α, FABP4, and PPAR-γ in differentiation medium. ∗, p < .05; ∗∗, p < .01. Abbreviations: Dex, dexamethasone; MA, megestrol acetate; n.s., no significant difference.