Table 3.
VCM exposure group |
Adjusted OR (95%CI) | ||
Control (n = 58) | Liver lesions (n = 58) | ||
GSTT1 | |||
Non-null | 31 (53.4%) | 37 (63.8%) | 1.0 (reference) |
Null 27 | (46.6%) | 21 (36.2%) | 0.65 (0.31-1.37) |
GSTM1 | |||
Non-null | 37 (63.8%) | 36 (62.1%) | 1.0 (reference) |
Null | 21 (36.2%) | 22 (37.9%) | 1.08 (0.51-2.29) |
CYP2E1 | |||
c1c1 | 43 (74.1%) | 27 (46.6%) | 1.0 (reference) |
c1c2/ c2c2 | 13/2 (25.8%) | 24/7 (53.4%) | 3.29 (1.51-7.20) b |
ALDH2 | |||
1-1 | 37 (63.8%) | 36 (62.1%) | 1.0 (reference) |
1-2/2-2 | 17/4 (36.2%) | 17/5 (37.9%) | 1.08 (0.51-2.29) |
ADH2 | |||
1-1 | 4 (6.9%) | 9 (15.5%) | 1.0 (reference) |
1-2/2-2 | 24/30 (93.1%) | 22/27 (84.5%) | 0.40 (0.12-1.39) |
Age (yr) | |||
< 35 | 41 (70.7%) | 35 (60.3%) | 1.0 (reference) |
≥ 35 | 17 (29.3%) | 23 (46.6) | 2.10 (0.76-3.43) |
Drinking | |||
No | 53 (91.4%) | 47 (81.0%) | 1.0 (reference) |
Yes | 5 (9.6%) | 11 (19.0%) | 2.48 (0.80-7.66) |
Smoking | |||
No | 40 (69.0%) | 41 (71.7%) | 1.0 (reference) |
Yes | 18 (31.0%) | 17 (29.3%) | 0.92 (0.42-2.04) |
P < 0.01 vs control.