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. 2005 Oct 7;11(37):5821–5827. doi: 10.3748/wjg.v11.i37.5821

Table 3.

Liver lesions status according to genotypes and variables of interest in VCM exposure group

VCM exposure group
Adjusted OR (95%CI)
Control (n = 58) Liver lesions (n = 58)
GSTT1
Non-null 31 (53.4%) 37 (63.8%) 1.0 (reference)
Null 27 (46.6%) 21 (36.2%) 0.65 (0.31-1.37)
GSTM1
Non-null 37 (63.8%) 36 (62.1%) 1.0 (reference)
Null 21 (36.2%) 22 (37.9%) 1.08 (0.51-2.29)
CYP2E1
c1c1 43 (74.1%) 27 (46.6%) 1.0 (reference)
c1c2/ c2c2 13/2 (25.8%) 24/7 (53.4%) 3.29 (1.51-7.20) b
ALDH2
1-1 37 (63.8%) 36 (62.1%) 1.0 (reference)
1-2/2-2 17/4 (36.2%) 17/5 (37.9%) 1.08 (0.51-2.29)
ADH2
1-1 4 (6.9%) 9 (15.5%) 1.0 (reference)
1-2/2-2 24/30 (93.1%) 22/27 (84.5%) 0.40 (0.12-1.39)
Age (yr)
< 35 41 (70.7%) 35 (60.3%) 1.0 (reference)
≥ 35 17 (29.3%) 23 (46.6) 2.10 (0.76-3.43)
Drinking
No 53 (91.4%) 47 (81.0%) 1.0 (reference)
Yes 5 (9.6%) 11 (19.0%) 2.48 (0.80-7.66)
Smoking
No 40 (69.0%) 41 (71.7%) 1.0 (reference)
Yes 18 (31.0%) 17 (29.3%) 0.92 (0.42-2.04)
b

P < 0.01 vs control.