Table 2. Results of sub-group meta-analysis using different genetic models.
Analysis models | Heterogeneity | Fixed | Random | Inference | |||
---|---|---|---|---|---|---|---|
I2 | P | OR | P | OR | P | ||
Caucasians | |||||||
GG vs. (GC + CC) | 77.15 | 0 | 1.011 | 0.797 | 0.989 | 0.911 | Not significant |
GG vs. GC | 86.11 | 0 | 0.838 | 0 | 0.793 | 0.088 | Not significant |
GG vs. CC | 73.54 | 0 | 2.398 | 0 | 1.852 | 0.011* | Significant association |
GC vs. CC | 90.2 | 0 | 4.408 | 0 | 2.388 | 0.023* | Significant association |
(GG + GC) vs. CC | 87.32 | 0 | 3.754 | 0 | 2.139 | 0.016* | Significant association |
East–Asians | |||||||
GG vs. (GC + CC) | 16.04 | 0.31 | 1.095 | 0.314 | 1.112 | 0.295 | Not significant |
GG vs. GC | 27.49 | 0.25 | 1.049 | 0.607 | 1.074 | 0.535 | Not significant |
GG vs. CC | 0 | 0.37 | 1.611 | 0.061 | 1.611 | 0.061 | Not significant |
GC vs. CC | 0 | 0.41 | 1.641 | 0.061 | 1.641 | 0.061 | Not significant |
(GG + GC) vs. CC | 0 | 0.39 | 1.596 | 0.064 | 1.596 | 0.064 | Not significant |
Mixed | |||||||
GG vs. (GC + CC) | 0 | 0.63 | 0.97 | 0.431 | 0.97 | 0.431 | Not significant |
GG vs. GC | 0 | 0.48 | 0.948 | 0.186 | 0.948 | 0.186 | Not significant |
GG vs. CC | 49.52 | 0.08 | 1.443 | 0.029 | 1.169 | 0.652 | Not significant |
GC vs. CC | 56.7 | 0.04 | 1.513 | 0.016 | 1.129 | 0.754 | Not significant |
(GG + GC) vs. CC | 51.01 | 0.07 | 1.451 | 0.026 | 1.163 | 0.669 | Not significant |
*Indicates statistical significance