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. 2015 Jun 25;5:11588. doi: 10.1038/srep11588

Table 2. Results of sub-group meta-analysis using different genetic models.

Analysis models Heterogeneity Fixed Random Inference
I2 P OR P OR P
Caucasians
GG vs. (GC + CC) 77.15 0 1.011 0.797 0.989 0.911 Not significant
GG vs. GC 86.11 0 0.838 0 0.793 0.088 Not significant
GG vs. CC 73.54 0 2.398 0 1.852 0.011* Significant association
GC vs. CC 90.2 0 4.408 0 2.388 0.023* Significant association
(GG + GC) vs. CC 87.32 0 3.754 0 2.139 0.016* Significant association
East–Asians
GG vs. (GC + CC) 16.04 0.31 1.095 0.314 1.112 0.295 Not significant
GG vs. GC 27.49 0.25 1.049 0.607 1.074 0.535 Not significant
GG vs. CC 0 0.37 1.611 0.061 1.611 0.061 Not significant
GC vs. CC 0 0.41 1.641 0.061 1.641 0.061 Not significant
(GG + GC) vs. CC 0 0.39 1.596 0.064 1.596 0.064 Not significant
Mixed
GG vs. (GC + CC) 0 0.63 0.97 0.431 0.97 0.431 Not significant
GG vs. GC 0 0.48 0.948 0.186 0.948 0.186 Not significant
GG vs. CC 49.52 0.08 1.443 0.029 1.169 0.652 Not significant
GC vs. CC 56.7 0.04 1.513 0.016 1.129 0.754 Not significant
(GG + GC) vs. CC 51.01 0.07 1.451 0.026 1.163 0.669 Not significant

*Indicates statistical significance