Table 2. Summary of CCL2, CCL4, CCR5, c-Jun, c-Fos Gene Expression in RT-PCR.
| Gene | Relative mRNA expression in RA ST (RA/control) | Fold | Relative mRNA expression on RA PB leukocytes (RA/control) | Fold |
|---|---|---|---|---|
| CCL2 | (10.91±1.11)/(1.52±0.61) | 7.18* | (5.85±14.23)/(3.07±3.79) | 1.91* |
| CC4 | (9.43±0.96)/(1.09±0.51) | 8.65* | (1.42±0.50)/(0.86±0.42) | 1.65* |
| CC5 | (7.46±1.21)/(1.09±0.40) | 6.84* | (1.53±0.82)/(1.12±0.53) | 1.36* |
| c-Jun | (20.80±0.87)/(1.02±0.24) | 20.40* | (5.60±9.30)/(1.65±181) | 3.39* |
| c-Fos | (5.38±1.69)/(1.87±0.05) | 2.88* | (2.81±1.82)/(0.72±0.41) | 3.90* |
RT-PCR, real-time polymerase chain reaction; mRNA, messenger RNA; RA, rheumatoid arthritis; ST, synovial tissues; PB, peripheral blood.
*p<0.05, n=6 (in ST) and n=10 (on leukocytes) for RA patients versus healthy control.