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. 2015 Jun 5;56(4):877–886. doi: 10.3349/ymj.2015.56.4.877

Table 3.

Comparison of Odds Ratios of T Allele rs7216389 in ORMDL3 between Early Onset and Adult Onset of Asthma

Study group Adults, early onset Adult onset
na/nc p value OR (95% CI) na/nc p value OR (95% CI)
Iceland 617/30898 1.4×10-9 1.44 (1.28, 1.63) 744/30898 0.064 1.11 (0.99, 1.23)
Australia 370/564 0.016 1.26 (1.04, 1.52) 226/564 0.22 0.87 (0.70, 1.08)
The Netherlands 156/1564 0.0081 1.37 (1.09, 1.73) 57/1564 0.55 1.12 (0.77, 1.63)
Korea 211/558 0.0049 1.49 (1.13, 1.96) 1176/558 0.35 1.08 (0.92, 1.28)
United Kingdom 81/241 0.07 1.39 (0.97, 1.99) 60/241 0.63 1.10 (0.74, 1.65)
Combined non-icelandic 818/2927 1.6×10-6 1.35 (1.19, 1.52) 1519/2927 0.74 1.02 (0.91, 1.15)
Combined all 1435/33825 1.5×10-14 1.40 (1.28, 1.52) 2263/33825 0.11 1.07 (0.99, 1.16)

na/nc, number of asthmatics and controls; OR, odds ratio; CI, confidence intervals.

Adapted from Halapi, et al.22