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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: J Mol Neurosci. 2015 Mar 12;56(3):663–672. doi: 10.1007/s12031-015-0533-6

Fig. 4.

Fig. 4

EGFR transactivation inhibitors. (A) Five mM NAC or Tiron (Tir) had no effect on basal EGFR tyrosine phosphorylation but inhibited the increase in EGFR transactivation caused by CCK8 addition to NCI-H727 cells. (B) The mean value ± S.E. of 3 experiments is indicated; p < 0.05, *; relative to control; ; p < 0.05,a; relative to CCK-8 using the Student’s t-test. (C) Ten µM PP2 or GM6001 (GM) had no effect on basal EGFR tyrosine phosphorylation but inhibited the increase in EGFR transactivation caused by CCK-8 addition to NCI-H727 cells. (D) The mean value ± S.E. of 3 experiments is indicated; p < 0.01, ** relative to control; p < 0.01, aa: relative to CCK-8 using the Student’s t-test.