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. 2015 Jun 25;5:11544. doi: 10.1038/srep11544

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Copyright © 2015, Macmillan Publishers Limited

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(A) Untreated MCF-7 cells exhibit normal structures. (B1) and (C1) Early apoptosis features, namely, blebbing and chromatin condensation as well as late apoptotic cells were detected after 24 hours of treatment with (A) and (B). (B2) and (C2) Late apoptosis and secondary necrosis were observed after 48 h treatment with (A) and (B), respectively (magnification: 200×). VI: Viable cells; CC: Chromatin condensation; BL: Blebbing of the cell membrane; LA: Late apoptosis; SN: Secondary necrosis.