Table 3. Regions that showed significant differences in FC between controls and patients with PNES.
MNI coordinates |
|||||||
---|---|---|---|---|---|---|---|
Brain regions | BA | Cluster size | Peak t-value | X | Y | Z | |
L Superior frontal gyrus | |||||||
Cluster 1 | R Paracentral lobule | 2 | 226 | 3.68 | 36 | −33 | 63 |
Cluster 2 | L Inferior frontal gyrus, orbital | 47 | 179 | 4.06 | −21 | 33 | −12 |
L Precuneus | |||||||
Cluster 1 | L Superior frontal gyrus, medial orbital | 10 | 194 | 3.19 | 0 | 51 | −9 |
L Paracentral lobule | |||||||
Cluster 1 | L Middle frontal gyrus | 9 | 184 | 4.73 | -33 | 36 | 42 |
Cluster 2 | R Supplementary motor area | 7/31 | 641 | 3.96 | 6 | −21 | 48 |
L Precuneus | 7 | 3.88 | −6 | −51 | 48 | ||
R Precuneus | 7 | 3.64 | 3 | −39 | 54 | ||
L Median cingulate gyrus | 31 | 3.55 | −9 | −30 | 45 | ||
R Median cingulate gyrus | 31 | 3.86 | 9 | −24 | 42 | ||
R Postcentral gyrus | |||||||
Cluster 1 | L Middle frontal gyrus | 9 | 257 | 5.28 | −33 | 33 | 42 |
Cluster 2 | L Superior parietal lobule | 7 | 176 | 3.57 | −33 | −72 | 54 |
L Supplementary motor area | |||||||
Cluster 1 | L Middle frontal gyrus | 9 | 111 | 4.61 | −33 | 33 | 42 |
Cluster 2 | R Anterior cingulate gyrus | 32 | 336 | 3.21 | 9 | 42 | −9 |
L Anterior cingulate gyrus | 32 | 2.66 | −6 | 36 | 9 | ||
R Triangular inferior frontal gyrus | |||||||
Cluster 1 | R Middle frontal gyrus | 9 | 202 | −4.56 | 39 | 15 | 60 |
Notes: Results were corrected by AlphaSim(all the clusters survived p < 0.05, a combined threshold of p < 0.01 with a minimum cluster sizes of 116,115,162,150,79 and 157 voxels, respectively ).The coordinates were showed in the Montreal Neurological Institute (MNI) standard space. PNES, psychogenic non-epileptic seizures; Hem, hemisphere; BA, Brodmann area; L, left; R, right.