Fig. 1.

Mesenteric and not femoral arteries stiffen with aging. Normalized passive inner diameter and stress-strain relationships of mesenteric (a, b, e, and f) and femoral (c, d, g, and h) arteries of Rln ^+/+ (closed symbols) and Rln ^−/− (open symbols) mice at 3 (circle), 6 (square), 12 (triangle), 18 (diamond), and 23 (inverted triangle) months of age. Values are mean ± SEM. *Significantly (P < 0.05) different to 3–18-month-old mice, ^#significantly (P < 0.05) different to 6–23-month-old mice, n = 6–9