Table 3:

Traditional and alternative methods of drug targeting approaches

ALTERNATIVE THERAPEUTICS
S.NO	Therapy	Methods	Affected functioning	Effect of Yogic practices	References
1	YOGA	Kirtan Kriya or listening to relaxation music	Depression, Cognitive function, telomerase activity	12 min per day for 8 weeks. Improved the cognitive function by increased telomerase activity	105
		Regular yoga practice	Chronic Diseases: pulmonological rheumatological, gastrointestinal, cardiovascular origin	Better overall health status and physical quality of life	106
HERBAL THERAPY
S. No	Therapy	Ingredients	Mechanism		Reference
2	HERBAL THERAPY	Ginkgo biloba	Effects on cerebral circulation and neuronal cell metabolism, on the muscarinic cholinergic system, and showed antioxidant activity		107–108
		Curcumin	Reduces oxidative damage and amyloid pathology in Alzheimer		109–110
		Huperzia serrata	Anticholinesterase (anti-ChE) alkaloids isolated from plants		111–112
		Icariin	Chronic cerebral hypoperfusion		113–114
		Garlic	Affects brain serotonin (5-hydroxytryptamine [5-HT]) levels		115
		Berries (flavonoids and polyphenols)	Antioxidants		116
		Ashwagandha	Upregulation of LDL-related protein, muscarinic acetylcholine receptor		117
		Indian Ginseng	Acetyl cholinesterase inhibitors		118–119
		Shankpushapi	Free radical scavenging and enzymes acetylcholinesterase, butyrylcholinestrase, glycogen synthase kinase-3		120
		Brahmi (Bacopa monniera)	Bacosides AS synaptic activity in memory improvement in inflammation and antioxidant status, reduction in beta amyloid and increases in metal chelation		121,122