. Author manuscript; available in PMC: 2015 Jun 25.

Published in final edited form as: Funct Integr Genomics. 2012 Feb 18;12(2):357–365. doi: 10.1007/s10142-012-0266-3

Table 2.

Selected Gene Ontology categories of biological processes significantly enriched with differentially expressed genes in black bear bone

GO category	Total genes on array	Changed genes	GO Miner		GSEA
			Enrichment	FDR	NES	FDR
Organ morphogenesis (GO:0009887)	400	34↑	2.400	<0.001	1.74	0.008
Skeletal development (GO:0001501)	119	14↑	3.268	0.008	1.59	0.077
Central nervous system development (GO:0007417)	218	18↑	2.305	0.030	1.35	0.189
Muscle tissue development (GO:0060537)	117	13↑	3.087	0.015	1.25	0.178
Cartilage development (GO:0051216)	33	6↑	5.051	0.038	1.57	0.074
Ossification (GO:0001503)	49	6↑	3.402	0.084	1.54	0.023
Phagocytosis (GO:0006909)	48	12↓	3.111	0.023	−1.43	0.094

Arrows indicate direction of gene regulation in hibernating animals

FDR false discovery rate, NES normalized enrichment score