Figure 1.
Manhattan plot of the GWAS meta-analysis for disc area in the combined analysis (n = 24,089 subjects of European and Asian ancestry). The plot shows −log10-transformed P-values for all single nucleotide polymorphisms. The red dotted horizontal line represents the genome-wide significance threshold of P < 5.0 × 10−8; the blue dotted line indicates P-value of 1 × 10−5. Gene loci in bold have been previously associated with disc area.