Table 1. Effect of western diet on plasma lipids.

Genotype	Diet	Weight (g)	Cholesterol (mg dl−1)	HDL (mg dl−1)	LDL (mg dl−1)	TGs (mg dl−1)	n
ApoE−/−	WD	34±3	1209±77	687±55	480±114	206±62	8
ApoE−/:Pak1−/−	WD	32±7	1007±133*	578±193	222±161*	106±53	7

HDL, high-density lipoprotein; LDL, low-density lipoprotein; TG, triglyceride; WD, Western diet.

*P< 0.01 versus ApoE^−/− mice.