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. Author manuscript; available in PMC: 2015 Jun 25.
Published in final edited form as: Microbiol Spectr. 2014 Dec;2(6):10.1128/microbiolspec.MDNA3-0038-2014. doi: 10.1128/microbiolspec.MDNA3-0038-2014

Table 1.

Stages of Lyme borreliosis

Localized (days to weeks post infection)
   Erythema migrans skin lesion
   Headache, malaise, fatigue, muscle and joint pain
Disseminated (weeks to months post infection)
   Secondary annular skin lesions
   Neuroborreliosis – meningitis, facial palsy, radiculoneuritis
   Migratory musculoskeletal pain
   Atrioventricular nodal heart block
   Lymphocytomaa
   Eye manifestations
Persistent (months to years post infection)
   Migratory arthritis of large joints
   Neuroborreliosis – meningitis, encephalitis, facial palsy, radiculoneuropathy, polyneuritis
   Atrioventricular nodal heart block
   Acrodermatitis chronica atrophicans skin lesionsa

Information from Steere et al. (3) and Müllegger et al. (5)

a

Found in Eurasia