Table 4. Multivariate analysis of patient survival by combined NDRG4 and p-AKT.
Combined NDRG4/p-AKT | Retrospective cohort | Prospective cohort | ||||
---|---|---|---|---|---|---|
n | Unadjusted HR (95% CI) | Adjusted HR (95% CI) | n | Unadjusted HR (95% CI) | Adjusted HR (95% CI) | |
NDRG4 + p-AKT− | 70 | 1.00 (reference) | 1.00 (reference) | 185 | 1.00 (reference) | 1.00 (reference) |
NDRG4 + p-AKT+ | 44 | 1.45 (1.04–3.79) | 1.62 (1.08–4.21) | 100 | 1.42 (1.08–2.96) | 1.57 (1.09–3.86) |
NDRG4 − p-AKT− | 68 | 1.51 (1.04–3.45) | 1.76 (1.13–3.43) | 148 | 1.39 (1.09–3.21) | 1.62 (1.14–3.58) |
NDRG4 − p-AKT+ | 90 | 2.12 (1.14–4.16) | 2.43 (1.16–4.26) | 275 | 2.06 (1.11–4.35) | 2.29 (1.15–4.18) |