Skip to main content
. 2015 Feb 25;6(10):7727–7740. doi: 10.18632/oncotarget.3115

Figure 5. Tumors of LFS family show impaired TP53 transcription.

Figure 5

RNA was extracted from blood from one unrelated control individual, TP53 intron 1 rearrangement carriers of the LFS family H2 and P13, OS lung metastasis of H2 and a lung adenocarcinoma derived cell line of P13. qRT-PCRs targeting all twelve TP53 isoforms (TP53) and short transcripts encoding for the N-terminus lacking isoforms Δ133p53 and Δ160p53 (TP53 delta) were performed in triplicates. Quantification cycle values (Cq) were normalized to GAPDH expression and are shown as fold change relative to control (y-axis). Error bars represent standard deviations. One representative of two experiments.