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Phylogenetic analysis of cognate and discrete acyltransferases (ATs), highlighting substrate specificities. Phylogenetic analysis was performed by the neighbor-joining method (Bruno et al., 2000). DiscreteATs form a loose but distinctive clade distant from the cognate ATs of prototypical PKSs. For discrete ATs, see Table 8.1 for references. For cognate ATs, NCBI accession numbers are given in parentheses.
