| # |
Downregulation: GO processes in common versus MCF7, SKBR3, and HCC1937 (107 genes) |
p value |
FDR |
|
|
1 |
Response to organic substance |
1.120E − 10 |
3.750E − 07 |
|
ERG1, IDI1, HSBP3, Ribonucleotide reductase, Galpha(s)-specific prostanoid GPCRs, MGMT, Cathepsin S, GREM2, MMP-13, SFRS3, BMP2, H-FABP, ACAT2, MGST3, IBP2, NNMT, CCL2, and DNAJA3
|
|
| 2 |
Regulation of immune complex clearance by monocytes and macrophages |
4.480E − 09 |
4.999E − 06 |
|
CCL2, CCL13, Galpha(q)-specific peptide GPCRs, Galpha(i)-specific peptide GPCRs
|
|
| 3 |
Positive regulation of immune complex clearance by monocytes and macrophages |
4.480E − 09 |
4.999E − 06 |
|
CCL2, CCL13, Galpha(q)-specific peptide GPCRs, and Galpha(i)-specific peptide GPCRs
|
|
|
4 |
Response to endogenous stimulus |
1.450E − 08 |
1.213E − 05 |
|
Ribonucleotide reductase, Galpha(s)-specific prostanoid GPCRs, MGMT, Cathepsin S, MMP-13, SFRS3, BMP2, H-FABP, MGST3, IBP2, NNMT, CCL2, CCL13, and Galpha(q)-specific peptide GPCRs
|
|
|
5 |
Response to acid |
2.446E − 08 |
1.638E − 05 |
|
Galpha(s)-specific prostanoid GPCRs, MGMT, BMP2, H-FABP, ACAT2, IBP2, CCL2, CCL13, Galpha(q)-specific peptide GPCRs, Galpha(i)-specific peptide GPCRs, PGD2R, PEDF (serpinF1), INSIG1, and CD9
|
|
| # |
Downregulation: metabolic networks in common versus MCF7, SKBR3, and HCC1937 (107 genes) |
p value |
FDR |
|
| 1 |
Steroid metabolism_cholesterol biosynthesis |
3.670E − 06 |
1.468E − 04 |
|
ERG1, IDI1, ACAT2, DHC24, MVD, and DHCR7
|
|
| 2 |
GalNAcbeta1-3Gal pathway |
5.291E − 04 |
1.058E − 02 |
|
Coagulation factor X, Galpha(q)-specific peptide GPCRs, Galpha(i)-specific peptide GPCRs, and CD13
|
|
| 3 |
N-Acyl-sphingosine phosphate pathway |
8.346E − 03 |
1.113E − 01 |
|
Galpha(q)-specific peptide GPCRs, PLAU (UPA), and MMP-1
|
|
| 4 |
Lipid metabolism_n-6 polyunsaturated fatty acid biosynthesis |
3.289E − 02 |
3.270E − 01 |
|
FADS2, FADS1
|
|
| 5 |
Glucosylceramide pathways and transport |
5.067E − 02 |
3.270E − 01 |
|
FADS2, FADS1
|
