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. 2015 Apr 28;42(8):1192–1201. doi: 10.1007/s00259-015-3048-z

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© The Author(s) 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — A threshold applied to the TcMAA SPECT image (a) defines the MAA-positive volume (b), and to the ^99mTc-sulphur colloid (SC) SPECT (c) defines the SC-positive volume (d). Coregistration of the two SPECT scans results in four compartments: f unirradiated functional liver (V _FL-UN), MAA-negative, SC-positive (blue), g tumour (V _T), MAA-positive SC-negative (red), h irradiated functional liver (V _FL-IR), MAA-positive SC-positive (purple), and tumour necrosis (V _NULL), MAA-negative SC-negative (black)