Table 5.
Reconstruction parameters that provided most accurate quantification over the assessments performed in this investigation, and the expected accuracy and standard deviations associated with measures of warm background and hot spheres for each. All measures are based on the results from day-0 imaging, where phantom background and hot sphere concentration were about 300 kBq/ml and 2,500 kBq/ml, respectively
| Vendor | Model | Recommended reconstruction for quantitative purposes | Error in warm background concentration measures (%) | Error in 37-mm hot sphere concentration measures (%) | ||
|---|---|---|---|---|---|---|
| Average ± SD | Range | Average ± SD | Range | |||
| GE Healthcare | Discovery 600 Discovery ST (E) Discovery RX | 3D OSEM with all-pass filter: e.g. 2i24s | −9 ± 10 | +4 – 29 | −34 ± 9 | −14 – 49 |
| GE Healthcare | Discovery 690 Discovery 710 | 3D OSEM with all-pass filter: e.g. 2i24s + RR + ToF | 1 ± 4 | +6 – 7 | −14 ± 9 | −5 – 28 |
| Philips | Gemini TF | 3D OSEM (BLOB OS TF) with no filter: 4i8s + ToF | −5 ± 2 | −4 – 6 | −22 ± 3 | −20 – 24 |
| Siemens | Biograph (various) | 3D OSEM with all-pass filter: e.g. 2i21s + RR (acquired in ‘PROMPTS + RANDOMS’ mode) | 2 ± 9 | +9 – 22 | −27 ± 5 | −20 – 40 |
| Siemens | Biograph mCT | 3D OSEM with all-pass filter: 2i21s + RR + ToF | −2 ± 6 | +4 – 9 | −16 ± 4 | −13 – 22 |