. Author manuscript; available in PMC: 2015 Jun 25.

Published in final edited form as: J Am Chem Soc. 2013 Oct 31;135(45):16968–16976. doi: 10.1021/ja406995j

Table 1.

Dataset used to measure the dielectric constant of proteins.

Protein (pH range)	Titr.group	pKa	side chain SASA (Å²)	# of identified CSPs ¹⁵N (¹H^N) Δδ_ef	# of absent CSPs ¹⁵N (¹H^N) Δδ_ef
ACBP (pH 3.0-8.9)	His14	7.1	36	9 (9)	70 (66)
ACBP (pH 3.0-8.9)	His30	6.7	6	33 (31)	46 (43)

A.v. Pc (pH 4.0-8.4)	His92	5.1	7	36 (34)	56 (58)
A.v. Pc (pH 4.0-8.4)	His61	7.1	14	30 (26)	62 (66)

P.l. Pc (pH 4.2-8.3)	His92	5.1	9	38 (32)	58 (63)

hGRX (pH 2.8-11.1)	Glu44	4.0	19	10 (8)	80 (80)
hGRX (pH 2.8-11.1)	Glu94	4.0	24	14 (11)	80 (80)

CexCD (pH 4.1-9.3)	His80	7.9	2	57 (46)	213 (232)

SNase (pH 1.4-11.1)	Asp21	6.5	2	33 (31)	72 (87)

Total				260 (228)	737 (775)