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. 2015 Jun 11;2015:859427. doi: 10.1155/2015/859427

Table 2.

Tropomyosin 1 gene RNA isoform expression in breast cancer cell lines.

Cell line RNA isoform expression
TMP1α TPM1β TPM1γ TPM1δ TMP1ε TPM1ζ TPM1η TPM1θ TPM1ι TPM1κ TPM1λ TPM1μ TPM1ν TPM1ξ GAPDH
Breast cancer
 HCC 1143 + +++ ++ + + ++++
 HCC 1187 + +++ ++ ++ + ++++
 BT 474 + +++ ++ + ++++
 mDAMB 157 + +++ ++ + + ++ ++++
 HCC 1806 ++ + + + ++++
 HCC 1419 + ++ ++ + + ++++
 mDAMB 453 ++ + ++ + ++++
 mDAMB 468 + +++ ++ + + + ++++
 MCF7 +++ + ++ ++++

MCF10A (normal breast) + +++ ++ + + + ++++
HCC 1143 (BL)+ ++++
HCC 1143 (BL)+ ++++
Adult heart ++++ + ++++
Fetal heart +++ ++ ++++

▲ = cell lines were analyzed by RNA-PCR for the indicated TPM1 isoforms. GAPDH RNA was analyzed as a control for baseline RNA expression. Expression was qualitatively recorded as either negative (−) or plus (+) to four pluses (++++).

= primary tumor; the rest were metastatic tumors.

+BL = B-lymphocyte cell lines.