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. 2015 Jun 24;10(6):e0129518. doi: 10.1371/journal.pone.0129518

Fig 3. Opthalmological evaluation of control and mutant mice.

Fig 3

Similar gross morphology of the anterior segment in control (A, A’) and Lrp2 FoxG1.cre-KO mutant littermates at P90 (B, B’). In some cases pupillary ectopia was observed in the mutants (C, C’). Fundus photographs of control (D, F) and mutant eyes (E, G) at P60 (D, E) and P180 (F, G) respectively show chorioretinal atrophy and peripapillary staphyloma. (H) Comparisons of intraocular pressure between control and mutant littermates at the indicated postnatal ages. Two-way ANOVA post hoc Tukey test was used, ***P<0.001, ns: not statistically significant, values are mean ± SEM of 10 animals per age and genotype.