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. 2015 Apr 11;14:80. doi: 10.1186/s12943-015-0352-y

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© Chow et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Anti-metastatic effect of Raf265 in combination with 5FU. Bioluminescence signals that were detected from the livers of mice with tumors from A. HT29 cells and B. HCT116 cells, and from the lungs of mice with tumors from C. HT29 cells and D. HCT116 cells were shown at the upper panel of each graph and the average bioluminescence signals from the corresponding organs with positive signals were plotted and shown at the lower panel of each graph. Data are presented as means ± SD from 6 mice and statistical analysis was performed by one-way ANOVA. *p < 0.05 versus the vehicle group with tumors from the corresponding cell lines.