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Structure of gut epithelium. In the small intestine, the epithelial stem cells located in the crypt differentiate into four cell types: the absorptive enterocytes, enteroendocrine cells, goblet cells, and paneth cells. In the colon, the epithelial stem cells are usually located in the lower parts of gut crypts and the differentiated cells migrate to the higher position and populate the colonic epithelial surface.
