Table 2.
Immunogen | IC50a |
---|---|
H3HA10 | 13479 |
H3HA10-IZ | 9082 |
H3HA10-Foldon | 16935 |
Naïve | 8287 |
aIC50 titer is the reciprocal of the sera dilution at which half-maximal entry inhibition was observed. Sera were collected 14 days after the boost and pooled.
The antibodies elicited by HA stem-fragment immunogens inhibited the entry of a heterologous H3 A/Wisconsin/67/2005 (with A/Udorn/307/1972 N2) influenza pseudotype virus.