. Author manuscript; available in PMC: 2015 Aug 26.

Published in final edited form as: N Engl J Med. 2015 Jan 28;372(9):885–887. doi: 10.1056/NEJMc1500960

Table 1. Fertility Rates in Women with Inherited Pathogenic Mitochondrial DNA Mutations, as Compared with Rates in the General Population.^*.

Age Range	Women with Mitochondrial DNA Mutations			General Population	P Value
	No. of Live Births	No. of Person-Years	Live Birth Rate (95% CI)	Live Birth Rate
			no./1000 person-yr
15–19 yr	17	761	22.3 (13.0–35.8)	32.2	0.14
20–24 yr	69	713	96.8 (75.3–122.5)	100.4	0.82
25–29 yr	91	651	139.8 (112.5–171.6)	117.6	0.12
30–34 yr	41	588	69.7 (50.0–94.6)	86.9	0.17
35–39 yr	12	516	23.3 (12.0–40.6)	38.5	0.08
40–44 yr	2	446	4.5 (0.54–16.2)	8.0	0.62
15–44 yr	232	3674	63.1 (55.2–71.8)	67.2	0.36

Values for women with inherited pathogenic mitochondrial DNA mutations are compared with the equivalent age- and era-weighted fertility rates (live births per 1000 women) and for the general population obtained from the U.K. Office for National Statistics.

Table 1. Fertility Rates in Women with Inherited Pathogenic Mitochondrial DNA Mutations, as Compared with Rates in the General Population.*.

Table 1. Fertility Rates in Women with Inherited Pathogenic Mitochondrial DNA Mutations, as Compared with Rates in the General Population.^*.