Fig 4.

Binding sites reads counts and comparison of bisulfite sequencing and MBD-Seq approaches a) Normalized reads in binding sites per condition. The first two boxplots represent the overall methylation level in the control and vaccinated groups. The boxplots marked with the + and - signs correspond to the DMRs with enriched methylation levels in the vaccinated and control clusters, accordingly b) DNA methylation levels expressed in -log2 fold change from bisulfite sequencing (y-axis) and MBD-Seq (x-axis) methods.