Table 4.

Regional topological properties in association with illness severity

Nodes with altered local clustering coefficient
High > Low	Right circular insula sulcus inferior	0.005
	Right insula short gyrus	0.01
	Right superior temporal gyrus	0.01
	Right inferior frontal (pars triangularis) gyrus	0.01
Low > High	Left angular gyrus	0.01
	Right occipital anterior sulcus	0.01
Nodes with altered local efficiency
High > Low	Right circular insula sulcus inferior	0.01
	Right circular insula sulcus superior	0.01
	Right short insula gyrus	0.01
	Right superior temporal gyrus	0.01
Low > High	NA
Nodes with altered degree
High > Low	Left frontal inferior orbital gyrus	0.01
	Left lateral fusiform gyrus	0.01
Low > High	Right inferior frontal sulcus	0.002

High: 20 subjects with positive loadings. Low: 21 subjects with negative loadings on illness severity factor. The severity factor was derived from the scores on 3 SSPI syndromes (reality distortion, psychomotor poverty and disorganization), total persistence, SOFAS and DSST scores