Figure 1. Macromolecular synthesis in the presence of ebselen.
Incorporation of radiolabeled precursors of DNA, RNA, protein, cell wall and lipid synthesis ([3H] thymidine, [3H] uridine, [3H] leucine, [14C] N-acetylglucosamine and [3H] glycerol, respectively) were quantified in S. aureus ATCC 29213. Results were expressed as percent of inhibition calculated based on the incorporation of radiolabeled precursors.